The way Cambodian patients and health professionals judge the priority of HIV-infected patients in relation to the allocation of antiretroviral drugs was examined. Participants were either HIV-infected patients attending the HIV/AIDS Care and Support Centre for People Living with HIV/AIDS in Phnom Penh (29 females and 21 males) or members of the staff (9 physicians, 6 pharmacists and 15 health counsellors and health educators). They were presented with stories of a few lines depicting a patient's situation and were instructed to (...) judge the extent to which the patient should be given priority for HIV drugs. The stories were composed according to a four within-subject factor design: (a) the patient's family responsibilities, (b) the severity of infection, (c) the time elapsed since the first consultation, and (d) the financial difficulties of the family. Most patients expressed the view that the drugs should be used for the patients who are most important from a familial point of view, namely, when the family contains small children and/or is already in a precarious financial condition. (shrink)

ABSTRACTAlthough a growing stream of research investigates the role of government in corporate social responsibility, little is known about how governmental CSR interventions interact in financial markets. This article addresses this gap through a longitudinal study of the socially responsible investment market in France. Building on the “CSR and government” and “regulative capitalism” literatures, we identify three modes of governmental CSR intervention—regulatory steering, delegated rowing, and microsteering—and show how they interact through the two mechanisms of layering and catalyzing. Our findings: (...) 1) challenge the notion that, in the neoliberal order, governments are confined to steering market actors—leading and guiding their behavior—while private actors are in charge of rowing—providing products and services; 2) show how governmental CSR interventions interact and are orchestrated; and 3) provide evidence that governments can mobilize financial markets to promote CSR. (shrink)

In this interview, Jean Greisch discusses the 1979 Colloquium Heidegger et la Question de Dieu, his original contribution to the published volume, and its impact on his later work. Greisch first situates the conference within the reception history of Heidegger as well as the critical advancements of Levinas and Derrida that made such a questioning of God palatable within the French philosophical context. He argues that theological thinking delivers an important challenge to philosophical thinking, and reflects on what such a (...) meeting point could mean. Finally he voices a double challenge to Heidegger, not only in his forgetting of the Hebraic tradition, but his complicity with Nazi antisemitism, while yet advising against a wholesale rejection of Heidegger’s insights. (shrink)

Le projet à l’origine de ce dossier thématique est celui d’une étude comparative de l’expérimentation telle qu’elle apparaît dans les sciences de la nature et dans les sciences humaines et sociales. Il illustre et prolonge les réflexions d’un séminaire de recherche sur le même sujet, organisé par Catherine Allamel-Raffin, qui s’est tenu pendant deux ans (2017-2018) à l’université de Strasbourg grâce à un financement de la Misha (Maison Interuniversitaire des Sciences de l’Homme – Alsace). Les...

In a recent contribution to this journal, Arjaliès (J Bus Ethics 92:57—78, 2010) suggests that the emergence of socially responsible investment (SRI) in France can be best described as a social movement with a collective identity that aimed to challenge the dominant logic of the financial market. Such an account is at odds with a body of empirical studies that approaches SRI in the French context as a process of market creation led by loosely coordinated actors with contradictory and conflicting (...) interests and values, who have mainly complied with—rather than opposed—the existing dominant financial logic of the asset-management field. In this comment, we build on this prior research to contest Arjaliès' perspective on both theoretical and empirical grounds, with the aim of highlighting the shortcomings of conflating social movements and other forms of collective actions in understanding the building of new markets in organization theory and SRI studies. We contend that in mistaking for social movement forms of collective actions that underpin the emergence of markets, scholars of organization theory may confuse distinct mechanisms in their explanation of SRI emergence across countries, overlook the complex dynamics and interactions of markets and social movements, and, most importantly, fail to evaluate the real political significance of SRI as an empirical phenomenon. We propose that future research on SRI distinguishes carefully "social-movement research as a theoretical framework" from "social movement as an empirical phenomenon" in order to avoid such drawbacks while benefiting from recent advances in social-movement research. (shrink)

Biological evolution provides a creative fount of complex and subtle adaptations, often surprising the scientists who discover them. However, because evolution is an algorithmic process that transcends the substrate in which it occurs, evolution’s creativity is not limited to nature. Indeed, many researchers in the field of digital evolution have observed their evolving algorithms and organisms subverting their intentions, exposing unrecognized bugs in their code, producing unexpected adaptations, or exhibiting outcomes uncannily convergent with ones in nature. Such stories routinely reveal (...) creativity by evolution in these digital worlds, but they rarely fit into the standard scientific narrative. Instead they are often treated as mere obstacles to be overcome, rather than results that warrant study in their own right. The stories themselves are traded among researchers through oral tradition, but that mode of information transmission is inefficient and prone to error and outright loss. Moreover, the fact that these stories tend to be shared only among practitioners means that many natural scientists do not realize how interesting and lifelike digital organisms are and how natural their evolution can be. To our knowledge, no collection of such anecdotes has been published before. This paper is the crowd-sourced product of researchers in the fields of artificial life and evolutionary computation who have provided first-hand accounts of such cases. It thus serves as a written, fact-checked collection of scientifically important and even entertaining stories. In doing so we also present here substantial evidence that the existence and importance of evolutionary surprises extends beyond the natural world, and may indeed be a universal property of all complex evolving systems. (shrink)

We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)

This study investigates the procedural learning, retention, and reactivation of temporal sensorimotor sequences in children with and without developmental coordination disorder. Twenty typically-developing children and 12 children with DCD took part in this study. The children were required to tap on a keyboard, synchronizing with auditory or visual stimuli presented as an isochronous temporal sequence, and practice non-isochronous temporal sequences to memorize them. Immediate and delayed retention of the audio-motor and visuo-motor non-isochronous sequences were tested by removing auditory or visual (...) stimuli immediately after practice and after a delay of 2 h. A reactivation test involved reintroducing the auditory and visual stimuli after the delayed recall. Data were computed via circular analyses to obtain asynchrony, the stability of synchronization and errors. Firstly, an overall deficit in synchronization with both auditory and visual isochronous stimuli was observed in DCD children compared to TD children. During practice, further improvements were found for the audio-motor non-isochronous sequence compared to the visuo-motor non-isochronous sequence in both TD children and children with DCD. However, a drastic increase in errors occurred in children with DCD during immediate retention as soon as the auditory stimuli were removed. Reintroducing auditory stimuli decreased errors in the audio-motor sequence for children with DCD. Such changes were not seen for the visuo-motor non-isochronous sequence, which was equally learned, retained and reactivated in DCD and TD children. All these results suggest that TD children benefit from both auditory and visual stimuli to memorize the sequence, whereas children with DCD seem to present a deficit in integrating an audio-motor sequence in their memory. The immediate effect of reactivation suggests a specific dependency on auditory information in DCD. Contrary to the audio-motor sequence, the visuo-motor sequence was both learned and retained in children with DCD. This suggests that visual stimuli could be the best information for memorizing a temporal sequence in DCD. All these results are discussed in terms of a specific audio-motor coupling deficit in DCD. (shrink)

L'ouvrage de Scarlett Beauvalet-Boutouyrie vient combler une lacune de l'historiographie en proposant la première synthèse sur le veuvage féminin dans la France d'Ancien Régime. Se plaçant dans une perspective d'histoire sociale, l'auteure a mené un travail ambitieux, résultat d'une habilitation à diriger des recherches, dans laquelle elle a volontairement croisé les approches. Partant d'une étude des discours, dans la première partie consacrée à la figure mythique de la veuve, elle ab...

Meditation refers to a family of self-regulation practices that focuses on training attention and awareness to foster psycho-emotional well-being and to develop specific capacities such as calmness, clarity, and concentration. We report a prospective convenience-controlled study in which we analyzed the effect of two components of Preksha Dhyāna – buzzing bee sound meditation and color meditation on healthy college students. Mahapran and leśya dhyāna are two Preksha Dhyāna practices that are based on sound and green color, respectively. The study population (...) represents a suitable target as college students experience different stress factors during the school year. This study measures the individual and combined effects of two techniques, on short-term memory, attention, and affect, in novice meditators. We used a battery of cognitive, performance, and compared results with baseline and control values. We found improved cognition, especially attention, short-term memory, and affect in terms of positivity and reduced negativity. Overall, the two techniques produced variable benefits and subjects showed improved scores over baseline for short-term memory, cognitive function, and overall wellbeing. Further studies are required to understand underlying mechanisms for the observed differences between the two techniques and to elucidate mechanisms underlying the more pronounced and global benefits observed with the combined techniques. These results underscore a need to examine individual components of meditation practices in order to individualize treatment approaches for attention disorders in young adults.Clinical Trail Registration:ClinicalTrials.gov Identifier: NCT03779269. (shrink)

Background: Recent changes to regulatory guidance in the US and Europe have complicated oversight of secondary research by rendering most uses of de-identified data exempt from human subjects oversight. To identify the implications of such guidelines for harms to participants and communities, this paper explores the secondary uses of one de-identified DNA sample collection with limited oversight: the Human Genome Diversity Project (HGDP)-Centre d'Etude du Polymorphisme Humain, Fondation Jean Dausset (CEPH) Human Genome Diversity Panel. Methods: Using a combination of keyword (...) and cited reference search, we identified English-language scientific articles published between 2002 and 2009 that reported analysis of HGDP Diversity Panel samples and/or data. We then reviewed each article to identify the specific research use to which the samples and/or data was applied. Secondary uses were categorized according to the type and kind of research supported by the collection. Results: A wide variety of secondary uses were identified from 148 peer-reviewed articles. While the vast majority of these uses were consistent with the original intent of the collection, a minority of published reports described research whose primary findings could be regarded as controversial, objectionable, or potentially stigmatizing in their interpretation. Conclusions: We conclude that potential risks to participants and communities cannot be wholly eliminated by anonymization of individual data and suggest that explicit review of proposed secondary uses, by a Data Access Committee or similar internal oversight body with suitable stakeholder representation, should be a required component of the trustworthy governance of any repository of data or specimens. (shrink)

Ce texte a déjà paru dans Sofistikê, n° 1, 2009. Nous remercions Stéphanie Orace de nous avoir autorisé à le reproduire ici. Le mouvement plus ou moins caché par lequel ce qui n'est pas encore est déjà ou est entièrement dans ce qui est […] s'appelle le rythme. Paul Valéry Comme l'a précisé Jean Mourot dès son introduction au Génie d'un style, expliquer le phénomène rythmique est une véritable gageure. Reste le parti de l'empirisme, pris finalement par Jean Mourot, et (...) qui revient non pas à cerner (...) - Poétique et Études littéraires – GALERIE – Nouvel article. (shrink)

Heidegger’s account of what it is to be a human being is compelling, but closed off to the idea of an Absolute. Yet Jean-Yves Lacoste argues it is possible even for Christianity to accept these atheistic structures of Dasein as native to the human condition. The initial closure of these structures to God cannot be erased, but one can marginalize them to make space for “liturgy,” or a relation to the Absolute. Lacoste offers asceticism as the most vivid illustration of (...) this liturgical marginalization, as a subversion of the structure of care. However, this immediately produces a contradiction. This subversion of care is itself a project of care: to succeed in marginalizing care only confirms it all the deeply. To rescue Lacoste from this vicious circle, I will draw upon Evagrius Ponticus, a 4th century desert monk known for his keen analysis of ascetic experience. Evagrius’ writings show how the subversion of care in ascesis can be completed only by its subversion in prayer. The interplay of these two moments, as elaborated through Evagrius’ writings, thus support Lacoste’s argument and offer a compelling illustration of these ideas at work. (shrink)

Mainstream political philosophy traditionally follows Jean-Jacque’s Rousseau’s lead, ‘taking men as they are and laws as they can be made’ (Rousseau, 1998, p. 3). The non-enforceable responsibiliti...

The Orthodox icon is often claimed as unique among images. Yet many proponents of this view, such as Leonid Ouspensky and Pavel Florensky, defend this singularity through a polemic against Western realism using a logic that culminates in a polemic against the world of experience. In this paper, I will use phenomenology to dismantle these two false dualities, against realist images and real experience, by uncovering the deeper concerns that motivate them. First, I draw on Merleau-Ponty’s phenomenology of painting to (...) collapse the dichotomy of carnal and spiritual images. Then, I use Jean-Luc Marion’s phenomenality of Revelation to reframe the dichotomy of worldly and spiritual experience. This broadened understanding of experience will serve as a starting point to refine our understanding of what is claimed by the icon, both in its function as an image and in the world it opens for those who approach it on its own terms. (shrink)

While it has become commonplace to use the term “icon” in philosophy of religion, it is an “icon” modeled after the resources of language. We find this for example in the recent Blackfriars article by Adam Glover, which despite its intention to treat the icon as an image, reduces it once again to a general form of reference which immediately feeds back into the linguistic. But might the icon have resources unique to its character as an image that can help (...) us understand what is meant by the paradoxical task of making visible the invisible God? This article takes up this task in conversation with the work of Jean-Luc Marion. (shrink)

Organized by Richard Kearney and Joseph S. O’Leary, the 1979 Colloquium Heidegger et la question de Dieu was of critical importance for the development of phenomenology of religion in France. This special issue introduces the event and its ensuing publication to the English-speaking world. The editors’ historical and thematic contextualizing essay is followed by contributions from six leading philosophers. Richard Kearney sets the stage by updating his original foreword, while Jean-Yves Lacoste presents the central moments in the history of Heidegger’s (...) complicated relationship to Christian thinking. Paul Ricoeur’s “Introductory Note” delivers a well-known challenge to Heidegger in a piece whose brevity belies its impact. Finally, three participants of the 1979 Colloquium, Joseph S. O’Leary, Jean Greisch, and Jean-Luc Marion, reflect back on the significance of this event and its role in developing their own groundbreaking work. The special issue closes with a brief reflection on where we find ourselves in philosophy today. (shrink)

Mainstream political philosophy traditionally follows Jean-Jacque’s Rousseau’s lead, ‘taking men as they are and laws as they can be made’ (Rousseau, 1998, p. 3). The non-enforceable responsibiliti...

In this interview, Jean-Luc Marion recalls the intellectual world of Paris in 1970s, reflecting on how his engagement with the ubiquitous “death of God” question led to the sketches of God without Being first presented at this 1979 Colloquium, and discusses the criticism it provoked not only from Heideggerians but also from Thomists. He discusses the reception history of phenomenology in France the reasons for the particular power it gained among thinkers of his generation. Finally, he recounts how his work (...) has led from the 1979 Colloquium through the “Theological Turn” and up to his forthcoming D’ ailleurs, la révélation, which he briefly previews here. Marion closes with words on originality, criticism, and the particular challenges of the contemporary world that await philosophical thinking today. (shrink)

Women in Antiquity: Real Women across the Ancient World. Edited by Stephanie Lynn Budin and Jean Macintosh Turfa. Rewriting Antiquity. London: Routledge, 2016. Pp. xxxvi + 1074, illus. $240.

This publication deals with the practical philosophy in Barhebraeus's enclyclopaedia of Aristotelian wisdom "Butyrum sapientiae". The three Syriac books on Ethics, Politics and Economy are unique and the only specimens of its kind, surviving in the Syriac language and literature.

"In this groundbreaking book Jean Walton subjects psychoanalysis to a sustained and highly illuminating ethnographic critique.

L’Angleterre du xviie siècle connut un intense bouillonnement politique et religieux dont le paroxysme se situe au milieu du siècle, lors de la première révolution anglaise. De profondes aspirations égalitaires s’exprimèrent au sein de certains groupes. Les sectes dissidentes qui émergèrent alors offrirent à des individus, jusque-là condamnés au silence par leur position sociale, la possibilité de prendre la parole et la plume pour s’exprimer publiquement. Les femmes furent nombreuses à se sa...

Alors que les travaux sur les cultures vestimentaires se sont multipliés et que les recherches historiques sur les cours aux époques médiévale et moderne sont fort nombreuses, de manière assez surprenante l’historiographie sur le vêtement de cour en Europe est restée peu fournie. Le colloque international tenu en 2009 au château de Versailles sur les « Cultures matérielles, cultures visuelles du costume dans les cours européennes (1400-1815) » se donnait donc pour objectif, sous la direction...

This publication deals with the practical philosophy in Barhebraeus's enclyclopaedia of Aristotelian wisdom "Butyrum sapientiae". The three Syriac books on Ethics, Politics and Economy are unique and the only specimens of its kind, surviving in the Syriac language and literature.

Cervical spinal cord injuries often lead to loss of motor function in both hands and legs, limiting autonomy and quality of life. While it was shown that unilateral hand function can be restored after SCI using a hybrid electroencephalography/electrooculography brain/neural hand exoskeleton, it remained unclear whether such hybrid paradigm also could be used for operating two hand exoskeletons, e.g., in the context of bimanual tasks such as eating with fork and knife. To test whether EEG/EOG signals allow for fluent and (...) reliable as well as safe and user-friendly bilateral B/NHE control, eight healthy participants as well as four chronic tetraplegics performed a complex sequence of EEG-controlled bilateral grasping and EOG-controlled releasing motions of two exoskeletons visually presented on a screen. A novel EOG command performed by prolonged horizontal eye movements to the left or right was introduced as a reliable switch to activate either the left or right exoskeleton. Fluent EEG control was defined as average “time to initialize” grasping motions below 3 s. Reliable EEG control was assumed when classification accuracy exceeded 80%. Safety was defined as “time to stop” all unintended grasping motions within 2 s. After the experiment, tetraplegics were asked to rate the user-friendliness of bilateral B/NHE control using Likert scales. Average TTI and accuracy of EEG-controlled operations ranged at 2.14 ± 0.66 s and 85.89 ± 15.81% across healthy participants and at 1.90 ± 0.97 s and 81.25 ± 16.99% across tetraplegics. Except for one tetraplegic, all participants met the safety requirements. With 88 ± 11% of the maximum achievable score, tetraplegics rated the control paradigm as user-friendly and reliable. These results suggest that hybrid EEG/EOG B/NHE control of two assistive devices is feasible and safe, paving the way to test this paradigm in larger clinical trials performing bimanual tasks in everyday life environments. (shrink)

Many meta-ethicists are alethists: they claim that practical considerations can constitute normative reasons for action, but not for belief. But the alethist owes us an account of the relevant difference between action and belief, which thereby explains this normative difference. Here, I argue that two salient strategies for discharging this burden fail. According to the first strategy, the relevant difference between action and belief is that truth is the constitutive standard of correctness for belief, but not for action, while according (...) to the second strategy, it is that practical considerations can constitute motivating reasons for action, but not for belief. But the former claim only shifts the alethist's explanatory burden, and the latter claim is wrong—we can believe for practical reasons. Until the alethist can offer a better account, then, I argue that we should accept that there are practical reasons for belief. (shrink)

With the growth of precision medicine research on health data and biospecimens, research institutions will need to build and maintain long-term, trusting relationships with patient-participants. While trust is important for all research relationships, the longitudinal nature of precision medicine research raises particular challenges for facilitating trust when the specifics of future studies are unknown. Based on focus groups with racially and ethnically diverse patients, we describe several factors that influence patient trust and potential institutional approaches to building trustworthiness. Drawing on (...) these findings, we suggest several considerations for research institutions seeking to cultivate long-term, trusting relationships with patients: Address the role of history and experience on trust, engage concerns about potential group harm, address cultural values and communication barriers, and integrate patient values and expectations into oversight and governance structures. (shrink)